| Item Type | Name |
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Academic Article
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Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40.
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Academic Article
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Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs.
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Concept
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Inhibitor of Differentiation Protein 2
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Concept
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Sequence Analysis, RNA
|
|
Concept
|
Ubiquitin-Protein Ligases
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Concept
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Interleukin-1alpha
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Concept
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Antigens, Differentiation, T-Lymphocyte
|
|
Concept
|
Sarcoma
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|
Concept
|
Down-Regulation
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Concept
|
Jurkat Cells
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Concept
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Lymphoma, T-Cell
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Concept
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Cell Movement
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Concept
|
Homeodomain Proteins
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Concept
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Nerve Sheath Neoplasms
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Concept
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Motivation
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Concept
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Smad1 Protein
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Concept
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Antigen Presentation
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Concept
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Pilot Projects
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Concept
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Membrane Glycoproteins
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Concept
|
HLA-A1 Antigen
|
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Concept
|
Hematopoietic Stem Cells
|
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Concept
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Sarcoma, Alveolar Soft Part
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|
Concept
|
Hepatocyte Growth Factor
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|
Concept
|
Antibodies, Anti-Idiotypic
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|
Concept
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Cancer Care Facilities
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|
Concept
|
Receptors, Antigen
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Concept
|
Membrane Transport Proteins
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Concept
|
Protein Structure, Tertiary
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Concept
|
Adaptor Proteins, Signal Transducing
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Concept
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Radiation Dosage
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Concept
|
Receptors, Interleukin-7
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|
Concept
|
Cell Death
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|
Concept
|
Pneumonia
|
|
Concept
|
Active Transport, Cell Nucleus
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|
Concept
|
Receptors, CXCR4
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|
Concept
|
Proto-Oncogene Proteins c-myc
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|
Concept
|
Tumor Necrosis Factors
|
|
Concept
|
Vesicular stomatitis Indiana virus
|
|
Concept
|
MAP Kinase Kinase 2
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|
Concept
|
Pleural Neoplasms
|
|
Concept
|
Cyclic AMP Response Element-Binding Protein
|
|
Concept
|
Carcinoma, Non-Small-Cell Lung
|
|
Concept
|
Chemokine CX3CL1
|
|
Concept
|
Aminopyridines
|
|
Concept
|
Antineoplastic Combined Chemotherapy Protocols
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|
Concept
|
Antigens, Ly
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|
Concept
|
Thalidomide
|
|
Concept
|
Cytokines
|
|
Concept
|
Angiogenesis Inhibitors
|
|
Concept
|
Tissue Distribution
|
|
Concept
|
Anus Neoplasms
|
|
Concept
|
Membrane Proteins
|
|
Concept
|
NK Cell Lectin-Like Receptor Subfamily K
|
|
Concept
|
Vascular Endothelial Growth Factor A
|
|
Concept
|
Follistatin
|
|
Concept
|
Age Factors
|
|
Concept
|
Receptors, Antigen, T-Cell, alpha-beta
|
|
Concept
|
beta-Defensins
|
|
Concept
|
Neutrophils
|
|
Concept
|
Precision Medicine
|
|
Concept
|
Peptidoglycan
|
|
Concept
|
Florida
|
|
Concept
|
Protein Subunits
|
|
Concept
|
Interleukin-10
|
|
Concept
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OX40 Ligand
|
|
Concept
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Prognosis
|
|
Concept
|
Databases, Factual
|
|
Concept
|
DNA-Binding Proteins
|
|
Concept
|
Thiazoles
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Nucleocytoplasmic Transport Proteins
|
|
Concept
|
Prefrontal Cortex
|
|
Concept
|
Lung Neoplasms
|
|
Concept
|
CD57 Antigens
|
|
Concept
|
Cyclin-Dependent Kinase 6
|
|
Concept
|
NF-kappa B
|
|
Concept
|
Kaplan-Meier Estimate
|
|
Concept
|
Interferon-gamma
|
|
Concept
|
Receptors, Androgen
|
|
Concept
|
Receptors, IgG
|
|
Concept
|
Nausea
|
|
Concept
|
Niacinamide
|
|
Concept
|
Interleukin-2 Receptor alpha Subunit
|
|
Concept
|
Receptors, Antigen, T-Cell
|
|
Concept
|
T-Cell Antigen Receptor Specificity
|
|
Concept
|
Proto-Oncogene Proteins c-rel
|
|
Concept
|
Flow Cytometry
|
|
Concept
|
Interleukin-9
|
|
Concept
|
Pain
|
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
|
Concept
|
CD8 Antigens
|
|
Concept
|
Tumor Suppressor Protein p53
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|
Concept
|
CD4 Antigens
|
|
Concept
|
Proportional Hazards Models
|
|
Concept
|
Vaccines, DNA
|
|
Concept
|
Frontal Lobe
|
|
Concept
|
Neoplasm Metastasis
|
|
Concept
|
Bone Morphogenetic Protein 7
|
|
Concept
|
Mitogen-Activated Protein Kinases
|
|
Concept
|
Drug Discovery
|
|
Concept
|
PTEN Phosphohydrolase
|
|
Concept
|
Quinazolines
|
|
Concept
|
Texas
|
|
Concept
|
Cell Division
|
|
Concept
|
Interleukin-13
|
|
Concept
|
Antigens, Differentiation
|
|
Concept
|
Drug Design
|
|
Concept
|
Luciferases, Firefly
|
|
Concept
|
CD40 Antigens
|
|
Concept
|
Polymers
|
|
Concept
|
Intercellular Adhesion Molecule-1
|
|
Concept
|
Angiogenesis Inducing Agents
|
|
Concept
|
Tumor Necrosis Factor Receptor Superfamily, Member 7
|
|
Concept
|
Chi-Square Distribution
|
|
Concept
|
Proto-Oncogene Proteins B-raf
|
|
Concept
|
Dogs
|
|
Concept
|
Receptors, OX40
|
|
Concept
|
Ligands
|
|
Concept
|
GTP-Binding Protein alpha Subunits, Gq-G11
|
|
Concept
|
Luminescent Proteins
|
|
Concept
|
Oncogene Protein p21(ras)
|
|
Concept
|
Confidence Intervals
|
|
Concept
|
Sirolimus
|
|
Concept
|
Dendritic Cells
|
|
Concept
|
Poly(ADP-ribose) Polymerases
|
|
Concept
|
Interferons
|
|
Concept
|
Feasibility Studies
|
|
Concept
|
Protein Kinase Inhibitors
|
|
Concept
|
STAT5 Transcription Factor
|
|
Concept
|
Disease-Free Survival
|
|
Concept
|
Herpesvirus 1, Human
|
|
Concept
|
Chromosomal Proteins, Non-Histone
|
|
Concept
|
Double-Blind Method
|
|
Concept
|
Proto-Oncogene Proteins c-bcl-2
|
|
Concept
|
Cyclin-Dependent Kinase Inhibitor p21
|
|
Concept
|
Cell Cycle Proteins
|
|
Concept
|
Mitogen-Activated Protein Kinase 1
|
|
Concept
|
Lymphocyte Function-Associated Antigen-1
|
|
Concept
|
Ovarian Neoplasms
|
|
Concept
|
Macrophages
|
|
Concept
|
Tryptophan Oxygenase
|
|
Concept
|
Tretinoin
|
|
Concept
|
Interferon Regulatory Factor-1
|
|
Concept
|
Peripheral Nervous System Neoplasms
|
|
Concept
|
Antigens, Tumor-Associated, Carbohydrate
|
|
Concept
|
Receptors, Fc
|
|
Concept
|
Alu Elements
|
|
Concept
|
Interleukin-17
|
|
Concept
|
Antibodies, Monoclonal
|
|
Concept
|
Cell Cycle
|
|
Concept
|
Receptors, Interleukin-6
|
|
Concept
|
Positron-Emission Tomography
|
|
Concept
|
Bacteremia
|
|
Concept
|
Macrophage Inflammatory Proteins
|
|
Concept
|
Chemokine CCL5
|
|
Concept
|
Cell Membrane
|
|
Concept
|
Receptor Protein-Tyrosine Kinases
|
|
Concept
|
Survival Analysis
|
|
Concept
|
Cluster Analysis
|
|
Concept
|
Green Fluorescent Proteins
|
|
Concept
|
Sex Factors
|
|
Concept
|
ras Proteins
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Vaccines, Synthetic
|
|
Concept
|
Antibody Formation
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Recombinant Fusion Proteins
|
|
Concept
|
Interleukin-1beta
|
|
Concept
|
Temporal Lobe
|
|
Concept
|
Inhibitor of Apoptosis Proteins
|
|
Concept
|
Evaluation Studies as Topic
|
|
Concept
|
Clone Cells
|
|
Concept
|
Pregnancy
|
|
Concept
|
Tumor Necrosis Factor Receptor Superfamily, Member 9
|
|
Concept
|
Placenta
|
|
Concept
|
Pulmonary Embolism
|
|
Concept
|
Luciferases
|
|
Concept
|
mRNA Cleavage and Polyadenylation Factors
|
|
Concept
|
Protein Structure, Quaternary
|
|
Concept
|
Immunoconjugates
|
|
Concept
|
Receptors, Interleukin-8B
|
|
Concept
|
Transduction, Genetic
|
|
Concept
|
Interferon-alpha
|
|
Concept
|
K562 Cells
|
|
Concept
|
Phosphoproteins
|
|
Concept
|
Receptor, ErbB-2
|
|
Concept
|
Th1 Cells
|
|
Concept
|
Cyclophosphamide
|
|
Concept
|
Interleukin-8
|
|
Concept
|
Interleukin-12 Subunit p40
|
|
Concept
|
Carcinoma, Renal Cell
|
|
Concept
|
Clinical Trials, Phase I as Topic
|
|
Concept
|
4-1BB Ligand
|
|
Concept
|
Interleukin-15
|
|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Ubiquitination
|
|
Concept
|
Carcinosarcoma
|
|
Concept
|
Hypoxia
|
|
Concept
|
Metabolic Clearance Rate
|
|
Concept
|
Immunoglobulin Variable Region
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Mitogen-Activated Protein Kinase Kinases
|
|
Concept
|
Radiopharmaceuticals
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Urinary Bladder Neoplasms
|
|
Concept
|
Receptors, Interleukin-2
|
|
Concept
|
Cell Survival
|
|
Concept
|
Treatment Outcome
|
|
Concept
|
Toll-Like Receptors
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Phenylurea Compounds
|
|
Concept
|
Cell Communication
|
|
Concept
|
RNA Editing
|
|
Concept
|
Cell Adhesion
|
|
Concept
|
Polyethylene Glycols
|
|
Concept
|
PAX5 Transcription Factor
|
|
Concept
|
Cell Adhesion Molecules
|
|
Concept
|
Forkhead Transcription Factors
|
|
Concept
|
Vascular Cell Adhesion Molecule-1
|
|
Concept
|
Receptors, Interferon
|
|
Concept
|
Venous Thromboembolism
|
|
Concept
|
Sodium-Phosphate Cotransporter Proteins
|
|
Concept
|
Nitric Oxide
|
|
Concept
|
Receptor, Interferon alpha-beta
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Receptors, Retinoic Acid
|
|
Concept
|
Antibodies
|
|
Concept
|
Oxidative Phosphorylation
|
|
Concept
|
Endothelial Cells
|
|
Concept
|
Medical Records
|
|
Concept
|
Cisplatin
|
|
Concept
|
Databases, Genetic
|
|
Concept
|
Rifampin
|
|
Concept
|
Liposarcoma
|
|
Concept
|
Receptors, CCR5
|
|
Concept
|
Culture Media
|
|
Concept
|
Nuclear Proteins
|
|
Concept
|
src-Family Kinases
|
|
Concept
|
Health Promotion
|
|
Concept
|
Chemical and Drug Induced Liver Injury
|
|
Concept
|
Recombinant Proteins
|
|
Concept
|
Phosphate Transport Proteins
|
|
Concept
|
STAT3 Transcription Factor
|
|
Concept
|
Antibodies, Viral
|
|
Concept
|
Inosine
|
|
Concept
|
DNA Copy Number Variations
|
|
Concept
|
Fibrosarcoma
|
|
Concept
|
Lymphoma
|
|
Concept
|
Toll-Like Receptor 4
|
|
Concept
|
Histocompatibility Antigens Class I
|
|
Concept
|
Pancreatic Neoplasms
|
|
Concept
|
T-Lymphocytes, Regulatory
|
|
Concept
|
Granulocyte Precursor Cells
|
|
Concept
|
Crohn Disease
|
|
Concept
|
Interleukin-4
|
|
Concept
|
Carcinoma, Squamous Cell
|
|
Concept
|
Transcription Factors
|
|
Concept
|
Endothelial Growth Factors
|
|
Concept
|
Mice, SCID
|
|
Concept
|
Neoplastic Cells, Circulating
|
|
Concept
|
Case-Control Studies
|
|
Concept
|
Neoplasm Proteins
|
|
Concept
|
Chemokine CCL2
|
|
Concept
|
Mucin-1
|
|
Concept
|
Toll-Like Receptor 8
|
|
Concept
|
Anniversaries and Special Events
|
|
Concept
|
Macrophage-1 Antigen
|
|
Concept
|
Histocompatibility Antigens Class II
|
|
Concept
|
Extracellular Signal-Regulated MAP Kinases
|
|
Concept
|
Neoplasm Staging
|
|
Concept
|
Predictive Value of Tests
|
|
Concept
|
Reproducibility of Results
|
|
Concept
|
Fas Ligand Protein
|
|
Concept
|
Gamma Rays
|
|
Concept
|
HLA-A Antigens
|
|
Concept
|
Killer Cells, Lymphokine-Activated
|
|
Concept
|
Prospective Studies
|
|
Concept
|
Dose-Response Relationship, Radiation
|
|
Concept
|
Kidney Neoplasms
|
|
Concept
|
3' Untranslated Regions
|
|
Concept
|
Antigen-Presenting Cells
|
|
Concept
|
Rats
|
|
Concept
|
beta 2-Microglobulin
|
|
Concept
|
Collagen
|
|
Concept
|
Proto-Oncogene Proteins p21(ras)
|
|
Concept
|
Sarcoma, Experimental
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Receptors, Immunologic
|
|
Concept
|
Drug Resistance, Neoplasm
|
|
Concept
|
Spleen
|
|
Concept
|
Randomized Controlled Trials as Topic
|
|
Concept
|
Stromal Cells
|
|
Concept
|
Carcinoma, Pancreatic Ductal
|
|
Concept
|
Genome-Wide Association Study
|
|
Concept
|
Immunization
|
|
Concept
|
Interleukin-12
|
|
Concept
|
Cyclin I
|
|
Concept
|
HLA Antigens
|
|
Concept
|
Proteomics
|
|
Concept
|
Leuprolide
|
|
Concept
|
Symporters
|
|
Concept
|
Viral Matrix Proteins
|
|
Concept
|
Tamoxifen
|
|
Concept
|
Tomography, X-Ray Computed
|
|
Concept
|
Cell Line
|
|
Concept
|
Nitric Oxide Synthase Type II
|
|
Concept
|
STAT1 Transcription Factor
|
|
Concept
|
Stomach Neoplasms
|
|
Concept
|
B7-1 Antigen
|
|
Concept
|
E-Selectin
|
|
Concept
|
3T3 Cells
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Enhancer Elements, Genetic
|
|
Concept
|
Protein Interaction Domains and Motifs
|
|
Concept
|
Receptors, Interleukin-21
|
|
Concept
|
MAP Kinase Kinase Kinases
|
|
Concept
|
Luminescent Measurements
|
|
Concept
|
Triazoles
|
|
Concept
|
Drug Interactions
|
|
Concept
|
Pneumonia, Viral
|
|
Concept
|
Antibodies, Neoplasm
|
|
Concept
|
Receptors, Lipoxin
|
|
Concept
|
Tumor Cells, Cultured
|
|
Concept
|
Carcinoma, Transitional Cell
|
|
Concept
|
Radiation Injuries
|
|
Concept
|
Biopsy
|
|
Concept
|
HLA-D Antigens
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Clinical Protocols
|
|
Concept
|
Lymphokines
|
|
Concept
|
Up-Regulation
|
|
Concept
|
Obesity
|
|
Concept
|
Logistic Models
|
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
|
Concept
|
Antibodies, Bacterial
|
|
Concept
|
Chromatin
|
|
Concept
|
Acquired Immunodeficiency Syndrome
|
|
Concept
|
Genes, bcl-2
|
|
Concept
|
Interleukin-5
|
|
Concept
|
CD11c Antigen
|
|
Concept
|
Receptors, Growth Factor
|
|
Concept
|
Cell Differentiation
|
|
Concept
|
Sodium-Phosphate Cotransporter Proteins, Type III
|
|
Concept
|
Clinical Trials as Topic
|
|
Concept
|
Receptors, CCR6
|
|
Concept
|
Toll-Like Receptor 9
|
|
Concept
|
DNA Primers
|
|
Concept
|
Bone Marrow Cells
|
|
Concept
|
Cyclin-Dependent Kinase 4
|
|
Concept
|
Vascular Endothelial Growth Factors
|
|
Concept
|
Statistics, Nonparametric
|
|
Concept
|
Pyrimidinones
|
|
Concept
|
Linear Models
|
|
Concept
|
Mitogen-Activated Protein Kinase 3
|
|
Concept
|
Proto-Oncogene Proteins c-met
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Transfection
|
|
Concept
|
Coronavirus Infections
|
|
Concept
|
Lymphatic Metastasis
|
|
Concept
|
Social Perception
|
|
Concept
|
Glycolysis
|
|
Concept
|
Antilymphocyte Serum
|
|
Concept
|
Paclitaxel
|
|
Concept
|
Ovalbumin
|
|
Concept
|
Chemokine CXCL1
|
|
Concept
|
Survival
|
|
Concept
|
Leucyl Aminopeptidase
|
|
Concept
|
Adenocarcinoma, Clear Cell
|
|
Concept
|
Vaccination
|
|
Concept
|
Sulfonamides
|
|
Concept
|
Adenosine Deaminase
|
|
Concept
|
Colony-Stimulating Factors
|
|
Concept
|
Von Hippel-Lindau Tumor Suppressor Protein
|
|
Concept
|
Risk Assessment
|
|
Concept
|
Structure-Activity Relationship
|
|
Concept
|
Receptors, Tumor Necrosis Factor
|
|
Concept
|
Complement C3
|
|
Concept
|
Chemokine CXCL10
|
|
Concept
|
MicroRNAs
|
|
Concept
|
Chemistry, Pharmaceutical
|
|
Concept
|
Risk Factors
|
|
Concept
|
Receptors, Vascular Endothelial Growth Factor
|
|
Concept
|
Chemokines
|
|
Concept
|
CD28 Antigens
|
|
Concept
|
Promoter Regions, Genetic
|
|
Concept
|
GTP-Binding Protein alpha Subunits
|
|
Concept
|
Proto-Oncogene Proteins
|
|
Concept
|
Myeloid Cells
|
|
Concept
|
Surface Plasmon Resonance
|
|
Concept
|
Viral Envelope Proteins
|
|
Concept
|
Osteosarcoma
|
|
Concept
|
Syndecans
|
|
Concept
|
Follow-Up Studies
|
|
Concept
|
Fibroblast Growth Factor 2
|
|
Concept
|
Killer Cells, Natural
|
|
Concept
|
Interferon Type I
|
|
Concept
|
Salmonella typhimurium
|
|
Concept
|
Immunohistochemistry
|
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Concept
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Injections, Intravenous
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Concept
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Cell Line, Tumor
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Concept
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Tumor Suppressor Proteins
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Concept
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RNA-Binding Proteins
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Concept
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HIV Infections
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Concept
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Rats, Inbred BUF
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Concept
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Viral Proteins
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Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Drug Antagonism
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Concept
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Repressor Proteins
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Concept
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Proteoglycans
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Concept
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Serum Albumin
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Concept
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Dendritic Cells, Follicular
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Concept
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Tryptophan
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Concept
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HSP90 Heat-Shock Proteins
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Concept
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B7-2 Antigen
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Concept
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Monocyte Chemoattractant Proteins
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Concept
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Neoplasm Recurrence, Local
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Concept
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DNA Fingerprinting
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Concept
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Protein-Arginine N-Methyltransferases
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Concept
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Genes, ras
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Concept
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Proto-Oncogene Proteins c-kit
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Concept
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Treatment Failure
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Concept
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CD40 Ligand
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Concept
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Complement System Proteins
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Concept
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Plasma Cells
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Concept
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Codon
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Concept
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CD3 Complex
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Concept
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HLA-DR Antigens
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Concept
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Lectins, C-Type
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Concept
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Interleukin-7
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Concept
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Retrospective Studies
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Concept
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Muromonab-CD3
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Concept
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Repetitive Sequences, Nucleic Acid
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Leukocyte Elastase
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Concept
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Toll-Like Receptor 2
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Concept
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HLA-A2 Antigen
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Concept
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Toll-Like Receptor 7
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Concept
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Cells, Cultured
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Concept
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Peritoneal Neoplasms
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Concept
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Interleukins
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Concept
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Pyridones
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Concept
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Stem Cells
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Concept
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Neoplasms, Unknown Primary
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Concept
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CD146 Antigen
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Concept
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Cell Separation
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Concept
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Myeloblastin
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Concept
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Nuclear Matrix-Associated Proteins
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Concept
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Proteins
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Concept
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Proto-Oncogene Proteins c-bcl-6
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Concept
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Multivariate Analysis
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Concept
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Mitogen-Activated Protein Kinase 14
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Concept
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Receptors, Formyl Peptide
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Concept
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Receptors, Virus
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Concept
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Granulocyte-Macrophage Colony-Stimulating Factor
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Concept
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Quality of Life
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Concept
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Antigens, CD
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Concept
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Microtubule-Associated Proteins
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Concept
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Transforming Growth Factor beta1
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Concept
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Neoplasm Invasiveness
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Concept
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MAP Kinase Kinase 1
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Concept
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Adenosine
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Concept
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Drug Synergism
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Concept
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Receptor-Interacting Protein Serine-Threonine Kinases
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Concept
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Monocytes
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Concept
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Natural Killer T-Cells
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Concept
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Interleukin-2
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Concept
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DNA Mutational Analysis
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Concept
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Biomedical Research
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Concept
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Endostatins
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Concept
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Pharmaceutical Vehicles
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Concept
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Endometrial Neoplasms
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Concept
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RNA Splice Sites
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Concept
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Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
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Concept
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Immunoglobulin G
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Concept
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Drug Resistance
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Concept
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RNA, Messenger
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Concept
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Protein Structure, Secondary
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Concept
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Cell Proliferation
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Concept
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Patient Care
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Concept
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Phosphorylation
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Concept
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Ribosomal Protein S6
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Academic Article
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HLA-A0201 positive pancreatic cell lines: new findings and discrepancies.
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Academic Article
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Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals.
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Academic Article
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Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice.
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Academic Article
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IFN-alpha enhances peptide vaccine-induced CD8+ T cell numbers, effector function, and antitumor activity.
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Academic Article
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Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy.
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Academic Article
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Characterization of human tumor cell lines transduced with the cDNA encoding either tumor necrosis factor alpha (TNF-a) or interleukin-2 (IL-2).
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Academic Article
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Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation.
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Academic Article
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Recognition of human colon cancer by T cells transduced with a chimeric receptor gene.
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Academic Article
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Human dendritic cells require multiple activation signals for the efficient generation of tumor antigen-specific T lymphocytes.
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Academic Article
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Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma.
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Academic Article
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Correspondence re R. Lapointe et al., CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 2003;63:2836-43.
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Academic Article
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Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors.
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Academic Article
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IL-21 synergizes with IL-7 to augment expansion and anti-tumor function of cytotoxic T cells.
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Academic Article
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Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients.
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Academic Article
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BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice.
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Academic Article
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BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.
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Academic Article
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Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8+ T-cell responses.
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Academic Article
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In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes.
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Academic Article
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The use of gene-modified tumor-infiltrating lymphocytes for cancer therapy.
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Academic Article
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Upregulation of tumor necrosis factor-alpha production by retrovirally transduced human tumor-infiltrating lymphocytes using trans-retinoic acid.
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Academic Article
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Cytokine secretion by genetically modified nonimmunogenic murine fibrosarcoma. Tumor inhibition by IL-2 but not tumor necrosis factor.
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Academic Article
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Functional and molecular characterization of tumor-infiltrating lymphocytes transduced with tumor necrosis factor-alpha cDNA for the gene therapy of cancer in humans.
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Academic Article
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Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases.
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Academic Article
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Prospective randomized trial of the treatment of patients with metastatic melanoma using chemotherapy with cisplatin, dacarbazine, and tamoxifen alone or in combination with interleukin-2 and interferon alfa-2b.
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Academic Article
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Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations.
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Academic Article
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Impact of cytokine administration on the generation of antitumor reactivity in patients with metastatic melanoma receiving a peptide vaccine.
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Academic Article
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CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral reservoir.
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Academic Article
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Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors.
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Academic Article
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Cell transfer therapy for cancer: lessons from sequential treatments of a patient with metastatic melanoma.
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Academic Article
|
Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo.
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Academic Article
|
Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes.
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Academic Article
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A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer.
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Academic Article
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Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific antitumor immune responses.
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Academic Article
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Antitumor activity of dual-specific T cells and influenza virus.
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Academic Article
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Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models.
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Academic Article
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Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenib.
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Academic Article
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Cytokines and angiogenic factors in patients with metastatic renal cell carcinoma treated with interferon-alpha: association of pretreatment serum levels with survival.
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Academic Article
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Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates.
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Academic Article
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T helper 17 cells promote cytotoxic T cell activation in tumor immunity.
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Academic Article
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Seventh annual meeting of the Italian Network for Tumor Biotherapy (NIBIT), Siena, 1-3 October 2009.
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Academic Article
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TGF-beta1 induces preferential rapid expansion and persistence of tumor antigen-specific CD8+ T cells for adoptive immunotherapy.
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Academic Article
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2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1.
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Academic Article
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Immunotherapy of melanoma: an update.
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Academic Article
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White paper on adoptive cell therapy for cancer with tumor-infiltrating lymphocytes: a report of the CTEP subcommittee on adoptive cell therapy.
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Academic Article
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Induction of TLR4-dependent CD8+ T cell immunity by murine ?-defensin2 fusion protein vaccines.
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Academic Article
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Antitumor activity mediated by CpG: the route of administration is critical.
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Academic Article
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Costimulation through the CD137/4-1BB pathway protects human melanoma tumor-infiltrating lymphocytes from activation-induced cell death and enhances antitumor effector function.
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Academic Article
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Impact of clinical and pathologic features on tumor-infiltrating lymphocyte expansion from surgically excised melanoma metastases for adoptive T-cell therapy.
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Academic Article
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Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma.
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Academic Article
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Increased CDC20 expression is associated with pancreatic ductal adenocarcinoma differentiation and progression.
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Academic Article
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Safety and activity of anti-PD-L1 antibody in patients with advanced cancer.
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Academic Article
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BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma.
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Academic Article
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PD-1 blockade enhances T-cell migration to tumors by elevating IFN-? inducible chemokines.
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Academic Article
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Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.
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Academic Article
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Persistent antigen at vaccination sites induces tumor-specific CD8? T cell sequestration, dysfunction and deletion.
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Academic Article
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Chemical castration of melanoma patients does not increase the frequency of tumor-specific CD4 and CD8 T cells after peptide vaccination.
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Academic Article
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Use of soluble recombinant TNF receptor to improve detection of TNF secretion in cultures of tumor infiltrating lymphocytes.
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Academic Article
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Interleukin-2-transduced lymphocytes grow in an autocrine fashion and remain responsive to antigen.
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Academic Article
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The genetic modification of T cells for cancer therapy: an overview of laboratory and clinical trials.
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Academic Article
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Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor gamma chain.
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Academic Article
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Improved gene transfer into human lymphocytes using retroviruses with the gibbon ape leukemia virus envelope.
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Academic Article
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Retroviral transduction of human dendritic cells with a tumor-associated antigen gene.
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Academic Article
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Current challenges in cancer gene therapy.
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Academic Article
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A T cell-independent antitumor response in mice with bone marrow cells retrovirally transduced with an antibody/Fc-gamma chain chimeric receptor gene recognizing a human ovarian cancer antigen.
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Academic Article
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Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation.
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Academic Article
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Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice.
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Academic Article
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CD40 ligand and lipopolysaccharide enhance the in vitro generation of melanoma-reactive T-cells.
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Academic Article
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Recurring cutaneous eruption in a patient with metastatic renal cell carcinoma being treated with high-dose interleukin 2.
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Academic Article
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CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells.
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Academic Article
|
Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen.
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Academic Article
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Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer.
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Academic Article
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Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6.
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Academic Article
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Improving antitumor immune responses by circumventing immunoregulatory cells and mechanisms.
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Academic Article
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Immunization against MUC18/MCAM, a novel antigen that drives melanoma invasion and metastasis.
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Academic Article
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Overexpression of interleukin 21 induces expansion of hematopoietic progenitor cells.
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Academic Article
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A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma.
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Academic Article
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Treating cancer by targeting the immune system.
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Academic Article
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Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses.
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Academic Article
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Melanoma cells express ICOS ligand to promote the activation and expansion of T-regulatory cells.
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Academic Article
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Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma.
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Academic Article
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Detection and characterization of a novel subset of CD8?CD57? T cells in metastatic melanoma with an incompletely differentiated phenotype.
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Academic Article
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Agonistic antibody to CD40 boosts the antitumor activity of adoptively transferred T cells in vivo.
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Academic Article
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Adoptive T-cell therapy using autologous tumor-infiltrating lymphocytes for metastatic melanoma: current status and future outlook.
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Academic Article
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Advances in the treatment of metastatic melanoma: adoptive T-cell therapy.
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Academic Article
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A new approach to simultaneously quantify both TCR a- and ?-chain diversity after adoptive immunotherapy.
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Academic Article
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Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
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Academic Article
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Characterizing the clinical benefit of ipilimumab in patients who progressed on high-dose IL-2.
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Academic Article
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Harnessing the power of the immune system to target cancer.
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Academic Article
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Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy.
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Academic Article
|
Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer--letter.
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Academic Article
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Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens.
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Academic Article
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Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma.
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Academic Article
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Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells.
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Academic Article
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Increased functional expression of transgene in primary human lymphocytes using retroviral vectors modified with IRES and splicing motifs.
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Academic Article
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Expression of a "self-"antigen by human tumor cells enhances tumor antigen-specific CD4(+) T-cell function.
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Academic Article
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A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer.
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Academic Article
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A novel strategy for rapid and efficient isolation of human tumor-specific CD4(+) and CD8(+) T-cell clones.
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Academic Article
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Complete response of stage IV anal mucosal melanoma expressing KIT Val560Asp to the multikinase inhibitor sorafenib.
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Academic Article
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Summary of the primer on tumor immunology and the biological therapy of cancer.
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Academic Article
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MART-1-specific melanoma tumor-infiltrating lymphocytes maintaining CD28 expression have improved survival and expansion capability following antigenic restimulation in vitro.
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Academic Article
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The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.
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Academic Article
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Bone marrow derived macrophages have polyamine and ectoenzyme phenotypes distinct from resident macrophages.
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Academic Article
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In vivo sensitivity of human melanoma to tumor necrosis factor (TNF)-alpha is determined by tumor production of the novel cytokine endothelial-monocyte activating polypeptide II (EMAPII).
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Academic Article
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Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity.
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Academic Article
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Expansion and characterization of T cells transduced with a chimeric receptor against ovarian cancer.
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Academic Article
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Generation of gene-modified T cells reactive against the angiogenic kinase insert domain-containing receptor (KDR) found on tumor vasculature.
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Academic Article
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Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma.
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Academic Article
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In vivo antitumor activity of interleukin 21 mediated by natural killer cells.
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Academic Article
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Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer.
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Academic Article
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PD-L1 expression in triple-negative breast cancer.
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Academic Article
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IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients.
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Academic Article
|
Pathways and therapeutic targets in melanoma.
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Academic Article
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Tumor-infiltrating lymphocyte therapy for melanoma: rationale and issues for further clinical development.
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Academic Article
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Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation.
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Academic Article
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Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma.
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Academic Article
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Manipulating the tumor microenvironment ex vivo for enhanced expansion of tumor-infiltrating lymphocytes for adoptive cell therapy.
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Academic Article
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Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis.
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Academic Article
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BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma.
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Academic Article
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STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
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Academic Article
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Molecular basis of antibody binding to mucin glycopeptides in lung cancer.
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Academic Article
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Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
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Academic Article
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STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity
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Academic Article
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Transduction and differentiation of dendritic cells from human hematopoietic progenitor cells
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Academic Article
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Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
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Academic Article
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Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells
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Academic Article
|
New insights on the role of CD8+CD57+ T-cells in cancer
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Academic Article
|
Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer
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Academic Article
|
T cells and T cell tumors efficiently generate antigen-specific cytotoxic T cell immunity when modified with an NKT ligand
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Academic Article
|
General discussion 3
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Academic Article
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BRAFV600E co-opts a conserved MHC class I internalization pathway to diminish antigen presentation and CD8+ T-cell recognition of melanoma
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Academic Article
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The authors reply
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Academic Article
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The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.
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Academic Article
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Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.
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Academic Article
|
The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression.
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Academic Article
|
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.
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Academic Article
|
Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.
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Academic Article
|
Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy.
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Academic Article
|
A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.
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Academic Article
|
T cells and T cell tumors efficiently generate antigen-specific cytotoxic T cell immunity when modified with an NKT ligand.
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Academic Article
|
New insights on the role of CD8(+)CD57(+) T-cells in cancer.
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Academic Article
|
Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer.
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Academic Article
|
BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties.
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Academic Article
|
Correlation of BRAF Mutation Status in Circulating-Free DNA and Tumor and Association with Clinical Outcome across Four BRAFi and MEKi Clinical Trials.
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Academic Article
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Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
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Academic Article
|
Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma.
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Academic Article
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Defective STAT1 activation associated with impaired IFN-? production in NK and T lymphocytes from metastatic melanoma patients treated with IL-2.
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Academic Article
|
Complementing T-cell Function: An Inhibitory Role of the Complement System in T-cell-Mediated Antitumor Immunity.
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Academic Article
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Selective inhibition of autoimmune exacerbation while preserving the anti-tumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn's disease: a case report.
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Academic Article
|
Loss of IFN-? Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.
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Academic Article
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Suppression of Type I IFN Signaling in Tumors Mediates Resistance to Anti-PD-1 Treatment That Can Be Overcome by Radiotherapy.
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Academic Article
|
Metastatic Melanoma Patient Had a Complete Response with Clonal Expansion after Whole Brain Radiation and PD-1 Blockade.
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Academic Article
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CpG-based immunotherapy impairs antitumor activity of BRAF inhibitors in a B-cell-dependent manner.
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Academic Article
|
IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation.
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Academic Article
|
Bypassing STAT3-mediated inhibition of the transcriptional regulator ID2 improves the antitumor efficacy of dendritic cells.
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Academic Article
|
Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8+ T Cells and Histone Acetyltransferases.
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Academic Article
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4-1BB Agonist Focuses CD8+ Tumor-Infiltrating T-Cell Growth into a Distinct Repertoire Capable of Tumor Recognition in Pancreatic Cancer.
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Academic Article
|
Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma.
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Academic Article
|
High-Throughput Screening of Myxoid Liposarcoma Cell Lines: Survivin Is Essential for Tumor Growth.
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Academic Article
|
Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.
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Academic Article
|
Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function.
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Academic Article
|
Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.
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Academic Article
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Successful treatment of arthritis induced by checkpoint inhibitors with tocilizumab: a case series.
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Academic Article
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Overexpressed PRAME is a potential immunotherapy target in sarcoma subtypes.
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Academic Article
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Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter.
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Academic Article
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T-cell Homing Therapy for Reducing Regulatory T Cells and Preserving Effector T-cell Function in Large Solid Tumors.
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Academic Article
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Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome.
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Academic Article
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Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'.
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Academic Article
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Utilizing T-cell Activation Signals 1, 2, and 3 for Tumor-infiltrating Lymphocytes (TIL) Expansion: The Advantage Over the Sole Use of Interleukin-2 in Cutaneous and Uveal Melanoma.
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Academic Article
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RNA editing derived epitopes function as cancer antigens to elicit immune responses.
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Academic Article
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Radiation Followed by OX40 Stimulation Drives Local and Abscopal Antitumor Effects in an Anti-PD1-Resistant Lung Tumor Model.
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Academic Article
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Association between melanoma and renal-cell carcinoma for sequential diagnoses: A single-center retrospective study.
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Academic Article
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A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade.
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Academic Article
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Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.
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Academic Article
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IL17A Blockade Successfully Treated Psoriasiform Dermatologic Toxicity from Immunotherapy.
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Academic Article
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A First-in-Human Study and Biomarker Analysis of NKTR-214, a Novel IL2R??-Biased Cytokine, in Patients with Advanced or Metastatic Solid Tumors.
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Concept
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Poly(ADP-ribose) Polymerase Inhibitors
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Concept
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RAW 264.7 Cells
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Concept
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Bevacizumab
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Concept
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Imatinib Mesylate
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Concept
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Infliximab
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Concept
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Dasatinib
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Concept
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Poly (ADP-Ribose) Polymerase-1
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Concept
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Proteogenomics
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Concept
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Epithelial Cell Adhesion Molecule
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Concept
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Hepatitis A Virus Cellular Receptor 2
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Concept
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Tertiary Lymphoid Structures
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Concept
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Myeloid-Derived Suppressor Cells
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Concept
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Whole Genome Sequencing
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Concept
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Ipilimumab
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Concept
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Positive Regulatory Domain I-Binding Factor 1
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Concept
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Research Report
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Concept
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Class I Phosphatidylinositol 3-Kinases
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Concept
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Antibodies, Monoclonal, Murine-Derived
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Concept
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Melanoma-Specific Antigens
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Concept
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gp100 Melanoma Antigen
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Concept
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MART-1 Antigen
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Concept
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Topoisomerase I Inhibitors
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Concept
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Single-Cell Analysis
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Concept
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High-Throughput Nucleotide Sequencing
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Concept
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Standard of Care
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Concept
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Cell Cycle Checkpoints
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Concept
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Transcriptome
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Concept
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Mutation Rate
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Concept
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HLA-DRB1 Chains
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Concept
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HLA-A24 Antigen
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Concept
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Neoplasm Grading
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Concept
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B7 Antigens
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Concept
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Real-Time Polymerase Chain Reaction
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Concept
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Inducible T-Cell Co-Stimulator Protein
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Concept
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B7-H1 Antigen
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Concept
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CTLA-4 Antigen
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Concept
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Inducible T-Cell Co-Stimulator Ligand
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Concept
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Programmed Cell Death 1 Receptor
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Concept
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Antibodies, Monoclonal, Humanized
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Concept
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Image-Guided Biopsy
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Concept
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RNA, Long Noncoding
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Concept
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Polycomb Repressive Complex 2
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Concept
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Carcinogenesis
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Concept
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Gene Ontology
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Concept
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Aurora Kinase A
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Concept
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Aurora Kinase B
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Concept
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Cdc20 Proteins
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Concept
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Spike Glycoprotein, Coronavirus
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Concept
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Triple Negative Breast Neoplasms
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Concept
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Cell- and Tissue-Based Therapy
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Concept
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Protective Factors
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Concept
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Response Evaluation Criteria in Solid Tumors
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Concept
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ErbB Receptors
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Academic Article
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First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1.
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Academic Article
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Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3K? Inhibition in PTEN Loss Melanoma.
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Academic Article
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Lymphocyte-specific kinase expression is a prognostic indicator in ovarian cancer and correlates with a prominent B cell transcriptional signature.
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Academic Article
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B cells and tertiary lymphoid structures promote immunotherapy response.
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Academic Article
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Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy.
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Academic Article
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Comprehensive T cell repertoire characterization of non-small cell lung cancer.
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Academic Article
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Circulating Tumor Cells and Early Relapse in Node-positive Melanoma.
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Academic Article
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Immuno-genomic landscape of osteosarcoma.
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Academic Article
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T-cell lymphoma secondary to checkpoint inhibitor therapy.
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Academic Article
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18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer.
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Academic Article
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Bempegaldesleukin (NKTR-214) plus Nivolumab in Patients with Advanced Solid Tumors: Phase I Dose-Escalation Study of Safety, Efficacy, and Immune Activation (PIVOT-02).
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Academic Article
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Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy).
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Academic Article
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Bone morphogenetic protein 7 promotes resistance to immunotherapy.
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Academic Article
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An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer.
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Academic Article
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Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers.
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Academic Article
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Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity.
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Academic Article
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Applications of CRISPR Genome Editing to Advance the Next Generation of Adoptive Cell Therapies for Cancer.
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Academic Article
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Influence of injection technique, drug formulation and tumor microenvironment on intratumoral immunotherapy delivery and efficacy.
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Academic Article
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Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators.
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Academic Article
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IL-1a Mediates Innate and Acquired Resistance to Immunotherapy in Melanoma.
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Academic Article
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Designed improvement to T-cell immunotherapy by multidimensional single cell profiling.
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Academic Article
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Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic melanoma.
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Academic Article
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Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations.
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Academic Article
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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.
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Academic Article
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Enhancer reprogramming in PRC2-deficient malignant peripheral nerve sheath tumors induces a targetable de-differentiated state.
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Academic Article
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Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma.
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Academic Article
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Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma.
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Academic Article
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Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses.
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Academic Article
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Evaluation of Antibody Response to SARS-CoV-2 mRNA-1273 Vaccination in Patients With Cancer in Florida.
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Academic Article
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Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity.
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Academic Article
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LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade.
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Academic Article
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Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy.
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Academic Article
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Multi-modal molecular programs regulate melanoma cell state.
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Academic Article
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Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort.
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Academic Article
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Author Correction: Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy.
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Academic Article
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Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer.
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Academic Article
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Safety and immunogenicity of a third dose of mRNA-1273 vaccine among cancer patients.
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Academic Article
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The T Cell Immunoscore as a Reference for Biomarker Development Utilizing Real-World Data from Patients with Advanced Malignancies Treated with Immune Checkpoint Inhibitors.
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Academic Article
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Efficacy and safety of autologous tumor-infiltrating lymphocytes in recurrent or refractory ovarian cancer, colorectal cancer, and pancreatic ductal adenocarcinoma.
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